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KMID : 0359920080270010127
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Korean Journal of Nephrology
2008 Volume.27 No. 1 p.127 ~ p.132
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A Case of Focal Segmental Glomerulosclerosis Associated with Renal Cell Carcinoma
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Jeong Hun
Lee Yong-Gu
Kim Hyo-Young
Kim Sang-Hoon
Son Myung-Su
Cho Yang-Hyun
Kim Hyung-Jong
Yang Dong-Ho
Lee Yong-Hee
Hong Soon-Won
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Abstract
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The association between malignancy and glomerular disease has been reported in older patients. Although the relationship between membranous glomerulonephritis or minimal change disease and solid tumors or hematologic malignancies, respectively, are known widely, focal segmental glomerulosclerosis have been described rarely in patients with solid tumors. We describe a patient with renal cell carcinoma who presented to nephrotic syndrome, volume overload and renal failure. On renal biopsy at contra-lateral kidney of renal cell carcinoma, the patient was diagnosed at focal segmental glomerulosclerosis. The proteinuria and renal function were ameliorated after resection renal cell carcinoma.
We suggest that the focal segmental glomerulosclerosis is associated with renal cell carcinoma. This is the first case of the clinical cause of focal segmental glomerulosclerosis associated with renal cell carcinoma of papillary type.
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KEYWORD
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Focal segmental glomerulosclerosis, Renal cell carcinoma, Nephrotic syndrome
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